设为首页 | 加入收藏
网站首页 本刊简介 编委会 投稿指南 过刊浏览 广告合作 网上订购 下载专区 联系我们  
恐惧联结的习得及其脑机制研究
作者:刘宏艳1  王倩2  胡治国3 
单位:1. 浙江理工大学心理学系 浙江杭州310018 
2.
 哈尔滨工业大学人文与社会科学学院心理系 黑龙江哈尔滨 150001 
3.
 杭州师范大学认知与脑疾病研究中心 浙江杭州 310015 
关键词:恐惧 联结学习 条件反射 脑机制 
分类号:R395.1
出版年,卷(期):页码:2011,19(6):766-768
摘要:

恐惧联结学习是保证有机体生存和适应的重要手段,主要表现为以下三种方式:亲身体验、社会观察和言语指导,习得之后会对认知和社会功能产生重要影响。脑损伤、脑功能成像及神经核团水平的研究均表明,恐惧联结的习得主要与杏仁核和海马等脑区有关。

Associative learning of fear is crucial for human survival and adaptation.In this review,we first introducedthe three ways that leads to the development of associative learning of fear,including self-experiencing,social observationand verbal instruction.Secondly,we showed that the acquisition of associative learning of fear had important influence onthe cognitive and social behaviors.The extant studies on the neural basis of associative learning of fear,including lesionstudies,neuroimaging studies and studies on nucleus neurons in certain areas,demonstrated the crucial role of the amygdalaand hippocampus in the associative learning of fear.

基金项目:
国家自然科学基金(30700234);中国博士后科学基金(20090460557)
作者简介:
参考文献:

[1] Hamm AO,Weike AI.The neuropsychology of fear learningand fear regulation.International Journal of Psychophysiology,2005,57:5-14.
[2] Hooker CL,Germine LT,Knight RT,et al.Amygdala responseto facial expressions reflects emotional learning.The Journal of Neuroscience,2006,26:8915-8922.
[3] Olsson A,Phelps EA.Social learning of fear.Nature Neuroscience,2007,10:1095-1102.
[4] Hermans D,Vansteenwegen D,Grombez G,et al.Expectancy-learning and evaluative learning in human classical conditioning:affective priming as an indirect and unobtrusivemeasure of conditioned stimulus valence.Behaviour Re -search and Therapy,2002,40:217-234.
[5] Petrovic P,Kalisch R,Pessiglione M,et al.Learning affectivevalues for faces is expressed in amygdale and fusiformgyrus.SCAN,2008,3:109-118.
[6] Baeyens F,Crombez G,De Houwer J,et al.No evidence formodulation of evaluative flavor -flavor associations in hu -mans.Learning and Motivation,1996,27:200-214.
[7] Olsson A,Nearing KI,Phelps EA.Learning fears by observingothers:the neural systems of social fear transmission.SCAN,2007,2:3-11.
[8] Olsson A,Phelps EA.Learned fear of "unseen" faces afterpavlovian,observational and instructed fear.PsychologicalScience,2004,15:821-828.
[9] 刘宏艳,胡治国,彭聃龄.情绪概念归类对喜好度评定的影响.中国临床心理学杂志,2010,18:139-141.
[10] Walther E,Nagengast B,Trasselli C.Evaluative conditioningin social psychology:Facts and speculations.Cognitionand Emotion,2005,19:175-196.
[11] Lim SL,Pessoa L.Affective learning increases sensitivity tograded emotional faces.Emotion,2008,8:96-103.
[12] Angrilli A,Mauri A,Palomba D,et al.Startle reflex andemotion modulation impairment after a right amygdala lesion.Brain,1996,119:1991-2000.
[13] Funayama ES,Grillon C,Davis M,et al.A double dissociationin the affective modulation of startle in humans:effectsof unilateral temporal lobectomy.Journal of Cognitive Neuroscience,2001,13:721-729.
[14] Morris JS,?hman A,Dolan RJ.Conscious and unconsciousemotional learning in the human amygdala.Nature,1998,393:467-470.
[15] Veit R,Flor H,Erb M,et al.Brain circuits involved in emotionallearning in antisocial behavio and social phobia inhumans.Neuroscience Letters,2002,328:233-236.
[16] Lim S,Padmala S,Pessoa L.Affective learning modulatesspatial competition during low-load attentional conditions.Neuropsychologia,2008,46:1267-1278.
[17] Phelps EA,O'Connor KJ,Gatenby JC,et al.Activation ofthe left amygdala to a cognitive representation of fear.NatureNeuroscience,2001,4:437-441.
[18] Rodrigues SM,Schafe GE,LeDoux JE.Molecular mechanismsunderlying emotional learning and memory in the lateralamygdala.Neuron,2004,44:75-91.
[19] Wilensky AE,Schafe GE,Kristensen MP,et al.Rethinkingthe fear circuit:the central nucleus of the amygdala is requiredfor the acquistion,consolidation,and expression of Pavlovian fear conditioning.The Journal of Neuroscience,2006,26:12387-12396.
[20] Wiltgen BJ,Sander MJ,Anagnostaras SG,et al.Context fearlearning in the absence of the hippocampus.The Journal ofNeuroscience,2006,26:5484-5491.
[21] Pham K,Mcewen BS,LeDoux JE,et al.Fear learning transientlyimpairs hippocampal cell proliferation.Neuroscience,2005,130:17-24.
[22] Doyere V,Redini-Del NC,Dutrieux G,et al.Potentiation ordepression of synaptic efficacy in the dentate gyrus is determinedby the relationship between the conditioned andunconditioned stimulus in a classical conditioning paradigmin rats.Behavioural Brain Research,1995,70:15-29.
[23] Sacchetti B,Lorenzini CA,Baldi E,et al.Long-lasting hippocampalpotentiation and contextual memory consolidation.European Journal Neuroscience,2001.13:2291-2298.
[24] Sacchetti B,Lorenzini CA,Baldi E,et al.Time-dependentinhibition of hippocampal LTP in vitro following contextualfear conditioning in the rat.European Journal Neuroscience,2002.15:143-150.
[25] Garcia R,Tocco G,Baudry M,et al.Exposure to a conditionedaversive environment interferes with long-term potentiationinduction in the fimbria -CA.3 pathway.Neuro -science,1998,82:139-145.
[26] De Houwer J.A conceptual and theoretical analysis of evaluativeconditioning.The Spanish Journal of Psychology,2007,10:230-241.
[27] Walther E,Gawronski B,Blank H,et al.Changing likesand dislikes through the back door:The US-revaluation effect.Cognition and Emotion,2009,23:559-917

服务与反馈:
文章下载】【加入收藏
您是第访问者

《中国临床心理学杂志》编辑部
地址:湖南省长沙市中南大学湘雅二医院内, 410011
电 话:0731-85292472    电子邮件:cjcp_china@163.com