中国临床心理学杂志

情绪刺激对高抑郁症状大学生工作记忆影响的NIRS研究

作者：吴文峰卢永彪周海波朱孝杰万里川王凡

单位：1. 贵州师范大学教育科学学院贵阳 550001 2. 湖南科技大学教育学院湘潭 411201 3. 湖南师范大学教育科学学院 410012

分类号：R395.1

出版年,卷(期):页码：2017,25(2):259-262

摘要：

目的：探索高抑郁症状大学生工作记忆受情绪刺激影响的脑神经活动特点，了解抑郁产生的脑认知机制。方法：采用近红外光学脑成像系统测量情绪图片呈现后、被试完成N-Back任务时，前额叶脑区含氧血红蛋白浓度变化。结果：正性和负性情绪图片呈现后，正常组被试前额叶右前部含氧血红蛋白浓度，2-Back任务显著高于1-Back任务；而高抑郁症状组没有显著差异。结论：依据情绪情景脱敏假设，研究推断，高抑郁症状大学生可能对情绪刺激不敏感，尤其对正性情绪刺激不敏感，这可能是引起高抑郁症状的重要原因之一。

Objective: To explore the characteristics of brain neural activity in working memory affected by emotional stimulations among the college students with high depressive symptoms. Methods: Measured the changes in the concentration of oxygenated hemoglobin(oxyHb) during picture presentation and during the n-back tasks in the prefrontal cortex (PFC) with a 38-channel near-infrared spectroscopy(NIRS) system. Results: The positive picture and negative picture affected the oxyHb changes in right anterior parts of the prefrontal cortex during the n-back tasks; the oxyHb changes during the 2-Back tasks were significantly greater rather than 1-Back tasks in the normal group of college students, especially after showing positive emotional pictures. However, no significant oxyHb changes were discovered in the group with high depressive symptom. Conclusion: Different oxyHb changes responding to working memory task between normal subjects and those with high depressive symptoms suggest that college students with high depressive symptoms may be insensitive to emotional stimulus, especially, to positive emotional stimulus, which possibly contributes to depressive symptoms.

基金项目：

贵州师范大学资助博士科研项目（0516019）；贵州阳明文化研究院贵州省教育厅高校人文社会科学研究基地项目（0516051）

作者简介：

参考文献：

1 Dolcos F, Iordan AD, Dolcos S. Neural correlates of emotioncognition interactions:a review of evidence from brain imaging investigations. Journal of Cognitive Psychology, 2011, 23(6):669-694
2 董云英, 周仁来, 高鑫. 积极情绪的唤醒程度对空间工作记忆的影响. 中国临床心理学杂志, 2014, 22(5):761-767
3 Andreotti C, Thigpen JE, Dunn MJ, et al. Cognitive reappraisal and secondary control coping:associations with working memory, positive and negative affect, and symptoms of anxiety/depression. Anxiety, Stress & Coping, 2013, 26(1):20-35
4 Chen C, Chen J, Dai L. Working Memory and Functional Neuroimaging in Patients with Depression. Psychology, 2015, 6(12):1438-1442
5 Brooks JO, Vizueta N, Penfold C, et al. Prefrontal hypoactivation during working memory in bipolar Ⅱ depression. Psychological Medicine, 2015, 45(08):1731-1740
6 Yoon KL, Lemoult J, Joormann J. Updating emotional content in working memory:A depression-specific deficit? Journal of Behavior Therapy and Experimental Psychiatry, 2014, 45(3):368-374
7 Joormann J, Gotlib IH. Emotion regulation in depression:relation to cognitive inhibition. Cognition and Emotion, 2010, 24(2):281-298
8 Joormann J. Cognitive inhibition and emotion regulation in depression. Current Directions in Psychological Science, 2010, 19(3):161-166
9 于斌, 乐国安, 刘惠军. 工作记忆能力与自我调控. 心理科学进展, 2014, 5:772-781
10 Ozawa S, Matsuda G, Hiraki K. Negative emotion modulates prefrontal cortex activity during a working memory task:a NIRS study. Frontiers in Human Neuroscience, 2014, 8(46):1-10
11 Dolcos F, Wang L, Mather M. Current Research and Emerging Directions in Emotion-Cognition Interactions. Frontiers in Integrative Neuroscience, 2014, 8(83):1-11
12 Inzlicht M, Bartholow BD, Hirsh JB. Emotional foundations of cognitive control. Trends in Cognitive Sciences, 2015, 19(3):126-132
13 Masataka N, Perlovsky L, Hiraki K. Near-infrared spectroscopy(NIRS) in functional research of prefrontal cortex. Frontiers in Human Neuroscience, 2015, 9:1-3
14 Perlman SB, Huppert TJ, Luna B. Functional Near-Infrared Spectroscopy Evidence for Development of Prefrontal Engagement in Working Memory in Early Through Middle Childhood. Cerebral Cortex, 2015, 139:1-10
15 龚辉, 李成军, 李婷, 等. 前额叶皮层工作记忆作用的近红外光学成像. 中国科学(G辑:物理学力学天文学), 2007, 1:110-117
16 张明园. 精神科评定量表手册. 湖南长沙:湖南科学技术出版社, 1998. 27-31
17 Harvey PO, Le Bastard G, Pochon JB, et al. Executive functions and updating of the contents of working memory in unipolar depression. Journal of Psychiatric Research, 2004, 38(6):567-576
18 Rose EJ, Ebmeier KP. Pattern of impaired working memory during major depression. Journal of Affective Disorders, 2006, 90(2):149-161
19 Wenzlaff RM, Rude SS, Taylor CJ, et al. Beneath the veil of thought suppression:Attentional bias and depression risk. Cognition & Emotion, 2001, 15(4):435-452
20 Gollan JK, Pane HT, Mccloskey MS, et al. Identifying differences in biased affective information processing in major depression. Psychiatry Research, 2008, 159(1):18-24
21 Bylsma LM, Morris BH, Rottenberg J. A meta-analysis of emotional reactivity in major depressive disorder. Clinical Psychology Review, 2008, 28(4):676-691
22 Feeser M, Schlagenhauf F, Sterzer P, et al. Context insensitivity during positive and negative emotional expectancy in depression assessed with functional magnetic resonance imaging. Psychiatry Research:Neuroimaging, 2013, 212(1):28-35
23 Moran EK, Mehta N, Kring AM. Emotional responding in depression:distinctions in the time course of emotion. Cognition & Emotion, 2012, 26(7):1153-1175
24 Rottenberg J, Gross JJ, Gotlib IH. Emotion context insensitivity in major depressive disorder. Journal of Abnormal Psychology, 2005, 114(4):627-639
25 Connolly ME, Gollan JK, Cobia D, et al. Reduced striatal activation in females with major depression during the processing of affective stimuli. Journal of Psychiatric Research, 2015, 68:384-391
26 Baddeley A, Banse R, Huang Y, et al. Working memory and emotion:Detecting the hedonic detector. Journal of Cognitive Psychology, 2012, 24(1):6-16

服务与反馈：

【文章下载】【加入收藏】