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海洛因依赖者环境诱发渴求感的相关因素研究
作者:李旭1  赵敏2  王祖承1  徐定3  张祎3 
单位:1. 上海第二医科大学精神医学教研室 上海 200025 
2.
 上海市精神卫生中心 
3.
 上海市劳教戒毒所 
关键词:海洛因依赖 环境诱发渴求感 
分类号:R395.4
出版年,卷(期):页码:2002,10(3):181-182
摘要:

目的 研究海洛因依赖者环境诱发渴求感的相关因素。方法 对87名男性劳教患者进行环境诱发实验,比较诱发成功组(n=25)与诱发失败组(n=62)在人口学资料、吸毒相关特征、戒毒相关资料等方面的差异。结果 诱发成功组的毒品依赖程度强于诱发失败组,平均戒断时间短于诱发失败组。父母有烟酒嗜好以及首次吸毒有“飘”感的戒毒者,更容易诱发渴求感。结论 海洛因依赖者对于环境诱发刺激具有不同的易感性。对于预防复吸具有指导意义。

Objective To determine factors related to cue-induced craving of heroin addicts.Methods 87 male heroin addicts in a correction camp were exposed to heroin-related stimuli0.25 addicts were induced successfully while 62 failed.Demographic characteristics,drug use features,abstinent features were compared between the addicted group and those failed.Results Induced addicts had higher drug dependence severity and shorter average abstinent period than failed subjects.Subjects with parental history of addiction or experienced "high" at initial stage of drug use were vulnerable to be induced.Conclusion Individual vulnerability to cue-induced stimuli is found among heroin addicts.This finding may help to shed light on relapse prevention.

基金项目:
作者简介:
参考文献:

[1] Sell LA.Neural responses associated with cue evoked emotional states and heroin in opiate addicts.Drug and Alcohol Dependence,2000,60:207-216
[2] Franken IH,de Haan HA,van der Meer CW.Cue reactivity and effects of cue exposure in abstinent posttreatment drug users.J Subst Abuse Treat,1999,16(1):81-85
[3] Bordnick PC,Schmitz JM.Cocaie craving:an evaluation across treatment phases.J Subst Abuse,1998,10(1):9-17
[4] Ehrman RN,Robbins SJ.Laboratory exposure to cocaine cues does not increase cocaine use by outpatient subjects.J Subst Abuse Treat,1998,15(5):431-435
[5] Carter BL,Tiffany ST.Meta-analysis of cue-reactivity in addiction resersrch.Addiction,1999,94(3):327-340
[6] Michael A.Methodogical Approaches to Craving Research:The measurement of drug craving .Addiction,2000,95(supplement2):189-210

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