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摘要：
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目的:引入国外的老年性痴呆生活质量量表(QOL-AD)修订版, 并分析其信度和效度。方法:将222例痴呆或轻微认知功能损害患者, 分别评定其生活质量、认知功能、日常生活功能、心理状况、精神症状等, 探讨它们之间的相关性, 并对QOL-AD的内部一致性予以检验。结果:QOL-AD的内部一致性系数α=0.9243;QOL-AD得分与认知功能正相关(r=0.593, MMSE; r=0.446, FOM; r=0.599, RVR; r=0.489, BD; r=0.518, DS), 与抑郁负相关(r=-0.316, HAMD-P), 与日常生活功能相关(r=-0.781, ADL), 与精神症状负相关(r=-0.504, BPRS)。结论:QOL-AD修订版具有良好的信度和效度, 对今后的研究有一定的帮助。
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Objective:To discuss the theoretical and practical issues of quality of life assessment in older adults with cognitive impairment, describe a new measure of quality of life for dementia, the QOL-AD(revised edition in Chinese), and examine the reliability and validity of this scale.Methods:The sample was composed of 222 patients with dementia or mild impaired cognitive. Each patient was rated for his/her quality of life by using the QOL-AD(Chinese Version). The functional and cognitive status, psychological state, physical function, and behavior problems of the patients were also assessed. Reliability and validity of the instrument were examined.Results:Reliability of the QOL-AD (revised edition in Chinese ) was fairly good. The internal consistency coefficient (ICC) was 0.9243. Validity was supported by correlation with measures of depression (r=-0.316,HAMD), daily functioning (r=-0.781), cognitive level (r =0.593,MMSE; r =0.446,FOM; r=0.599,RVR; r =0.489,BD; r=0.518,DS), and psychiatric symptom (r =-0.504,BPRS).Conclusions:The QOL-AD (revised edition) seems to be reliable and valid for assessment of individuals with cognitive impairment. It's helpful to further research in dementia.
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基金项目：
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广东省医学科学技术研究基金(项目号:WSTJJ20031201422228197502195610)
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作者简介：
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参考文献：
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