<p><b>Objective</b>: To explore the influence of dysfunctional attitudes, self-esteem and stress on depression symptoms in grade 7 students, the key point was to explore the moderate effects of dysfunctional attitude and self-esteem on the relation of stress and depression. <b>Methods</b>: Children's Hassles Scale, Children's Dysfunctional Attitudes Scale Revised,Self-Esteem Scale and Children's Depression Inventory were used to test 324 grade 7 students 5 times, with a 2 month interval and analysis of multilevel linear model was adopted. <b>Results</b>: For cognitive factors of dysfunctional attitude and self-esteem, there was no significant moderate effect on the relationship between stress and depressive symptoms. Conclusion:Beck's cognitive theory might be not adapted to Chinese adolescents in 7th grade stage, and it indicates that an adolescent's cognitive development difference might exist between East and West.</p>
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