中国临床心理学杂志

妇科恶性肿瘤住院患者心理弹性与癌因性疲乏的关系：正负性情绪的中介作用

作者：朱红卫李芳李清华

单位：1. 河北医科大学第四医院妇瘤科石家庄 050011 2. 石家庄市第一医院手术室石家庄 050000

分类号：R395.2

出版年,卷(期):页码：2017,25(4):772-775

摘要：

目的：分析妇科恶性肿瘤患者心理弹性、正负性情绪和癌因性疲乏的关系，并探讨正性和负性情绪在心理弹性与癌因性疲乏间的中介作用。方法：选取河北省某三级甲等医院妇科恶性肿瘤住院患者141例，采用一般资料调查表、心理弹性量表（CD-RISC10）、癌症疲乏量表（CRF）及正负性情绪量表（PANAS）进行调查。应用结构方程模型探讨正负性情绪在心理弹性与癌因性疲乏间的中介作用，并用Bootstrap方法进行中介效应检验。结果：妇科恶性肿瘤患者的CRF评分为25.1±7.8。心理弹性评分与CRF评分及其各维度呈负相关（r=-0.31~-0.44，P<0.01）；正性情绪与CRF评分及其各维度呈负相关（r=-0.21~-0.60，P<0.01）；负性情绪与CRF评分及其各维度呈正相关（r=0.38~0.63，P<0.01）。Bootstrap检验结果显示间接效应的95% CI为（-0.14~-0.52，P<0.001），说明正负性情绪在心理弹性与癌因性疲乏间存在中介效应。结论：妇科恶性肿瘤患者存在癌因性疲乏的问题，心理弹性、正负性情绪是影响癌因性疲乏的因素，正负性情绪可以中介心理弹性与癌因性疲乏的关系。

Objective: To examine the relationship among resilience, positive and negative affect and cancer-related fatigue in patients with Gynecology malignant tumor, and to examine the mediating effect of positive and negative affect between resilience and cancer-related fatigue. Methods: Totally 141 patients with Gynecology malignant tumor were selected. The Connor-Davidson Resilience Scale(CD-RISC10), Positive and negative affect scales(PANAS), and Cancer Fatigue Scale(CRF) were used to assess the resilience, positive and negative affect and cancer-related fatigue respectively. Results: CD-RISC10 scores were negatively correlated with CRF scores and its subscales(r=-0.31~-0.44, P<0.01), the scores of positive affect were negatively correlated with CRF scores and its subscales(r=-0.21~-0.60, P<0.01), and negative affect scores were positively correlated with CRF scores and its subscales(r=0.38~0.63, P<0.01). Furthermore, Positive and negative affect mediated the relationship between resilience and cancer-related fatigue. Conclusion: Patients with Gynecology malignant tumor have severe cancer-related fatigue. Positive and negative affect could mediate the relationship between resilience and cancer-related fatigue.

基金项目：

河北省医学科学研究重点课题（20110512）

作者简介：

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