中国临床心理学杂志

Effects of Personality Traits and Serum Lipid Levels on Myocardial Enzyme of Angina Patients

作者：WANG Yi-he DU Jin-ling Angie LeRoy LIU De-xiang LU Qian PAN Fang

单位：1. Department of Neurology School of Clinical Medicine Shandong University Jinan 250012 China 2. Department of Heart Disease Qilu Hospital of Shandong University Jinan 250012 China 3. Department of Psychology University of Houston Houston TX 77204 U. S. A 4. Department of Medical Psychology School of Basic Medical Science Shandong University Jinan 250012 China

关键词：Personality trait Myocardial enzymes Lipid

分类号：R395.1

出版年,卷(期):页码：2017,25(6):1048-1053

摘要：

目的：探讨人格特征和血脂水平对心绞痛患者心肌酶的影响。方法：采用调查法对45例不稳定型心绞痛患者、60例稳定型心绞痛患者和50例健康人进行A型和D型人格问卷检测，同时检测血脂、肌钙蛋白（ICTNI）、肌酸激酶同工酶（CKMB）、乳酸脱氢酶（LDH）及乳酸脱氢酶1（LDH₁）水平。结果：与稳定型心绞痛和健康对照组比较，不稳定型心绞痛患者血清高密度脂蛋白水平显著降低；A型人格和D型人格得分、血清心肌酶水平显著升高。血清高密度脂蛋白水平与LDH₁显著负相关，时间紧迫感与血清LDH、LDH₁水平显著正相关，竞争和敌意与血清LDH水平显著正相关；D型人格特征与血清心肌酶水平无显著相关。高密度脂蛋白、时间紧迫感、竞争和敌意对心肌酶的效应值分布在0.125-0.039之间，为中等和较小效应值。结论：血清高密度脂蛋白、时间紧迫感和敌意与冠心病心肌损伤密切相关。

Objective:To examine the effects of personality traits and serum lipid levels on myocardial enzyme of angi-na patients. Methods:Total 155 subjects including 45 unstable angina patients, 60 stable angina patients and 50 healthy individuals were enrolled in the study. Type A personality, type D personality were assessed. Blood samples were taken to assess levels of serum lipid and myocardial enzyme including troponin I(CTNI), creatine kinase isoenzyme(CKMB), lactate dehydrogenase(LDH) and lactate dehydrogenase1(LDH₁). Results:Unstable angina patients had lower level of serum highdensity lipoprotein(HDL), higher sub-dimensions scores of type A and type D, and higher level of serum myocardial enzyme than stable angina patients and the healthy control. HDL was negatively correlated with LDH₁, Time Hurry was positively correlated with LDH and LDH₁, Competitive and Hostility were positively correlated with LDH. There was no significant as-sociation between type D personality and serum myocardial enzyme level. The η² of HDL and those personality traits on se-rum myocardial enzyme ranged from 0.125 to 0.039, indicating both HDL and personality traits had medium or small size ef-fects on serum myocardial enzyme levels. Conclusion:Lower level of serum HDL, Time Hurry and Hostility of type A per-sonality may contribute to myocardial injury in CHD.

基金项目：

济南市高校创新基金（201202227）

作者简介：

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