中国临床心理学杂志

术后正负性情绪对女性乳腺癌患者预后的影响

单位：1. 中南大学湘雅二医院医学心理中心长沙 410011 2. 中南大学湘雅二医院神经外科长沙 410011

分类号：R395.6

出版年,卷(期):页码：2018,26(2):383-386

摘要：

目的：探讨术后正负性情绪对女性乳腺癌患者预后的影响。方法：使用正负性情绪量表对277例女性乳腺癌患者术后一周的正、负性情绪进行评定，并收集患者一般人口学资料和临床病理资料。5年后，采用电话随访了解患者生存情况。采用Kaplan-Meier法计算生存率，采用Log-rank检验及Cox回归分析分别对分类变量和连续变量进行预后因素分析。结果：乳腺癌患者5年生存率为75.45%。淋巴结分期、长期居住地、正性情绪、负性情绪均为乳腺癌预后的影响因素（均P<0.001）。但控制淋巴结分期和长期居住地后，正性情绪仍显著影响患者预后（RR=0.756；95% CI 0.701-0.815；P<0.001），而负性情绪对预后的影响不再显著。结论：术后情绪影响乳腺癌预后，其中正性情绪对预后的影响比负性情绪更加重要。

Objective:To examine whether and how post-surgery positive affect and negative affect influence the prog-nosis of women with breast cancer. Methods:In total, 277 women with breast cancer completed a form for socio-demo-graphic and clinical information as well as the Chinese version of Positive and Negative Affect Scale. Kaplan-Meier method was conducted for survival analysis. Log-rank test and Cox regression analysis were conducted respectively for categorical variable and continuous variable. Results:The five-year survival rate for patients was 75.45%. The results of Log-rank test showed that there were significant differences between survival and non-survival patients in AJCC nodes pathologic sta-tus and long-term residence place(all P<0.01). The results of Cox regression analysis showed that post-surgery positive af-fect significantly predicted prognosis of women with breast cancer after controlling significant prognostic factors in univari-ate analysis(RR=0.756; 95%CI 0.701-0.815; P<0.001) while the influence of negative affect was not significant. Conclusion:Post-surgery emotion influences the prognosis of women with breast cancer. Notably, the influence of positive affect on prognosis of breast cancer is greater in comparison with negative affect.

基金项目：

国家“十一五”科技支撑计划课题基金（2009BAI77B06）资助

作者简介：

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