中国临床心理学杂志

男/女精神分裂症患者攻击行为的预测因素

单位：1. 深圳市第六人民医院临床心理科深圳 518052 2. 深圳市南山区慢性病防治院深圳 518054

分类号：R395.2

出版年,卷(期):页码：2017,25(2):217-220

摘要：

目的：探讨男/女精神分裂症患者攻击行为的预测因素。方法：随机抽取精神分裂症患者170例评估其一般资料、社会支持、自我效能、临床症状、外显攻击行为并检测其血清皮质醇，比较检测6个月后有攻击行为的男/女精神分裂症患者与无攻击行为的男/女患者首次检测时的相关资料，并分析男/女患者6个月后攻击行为的预测因素。结果：男性患者阳性症状，阴性症状、皮质醇与其6个月后的攻击行为相关，女性患者的攻击行为，阳性症状、皮质醇与其6个月后的攻击行为相关。结论：精神分裂症患者的攻击行为、阳性症状、阴性症状、皮质醇水平可预测其6个月后的攻击行为。

Objective: To explore the predictive factors of Male/Female schizophrenia patients' aggressive behavior. Methods: 170 schizophrenia patients were chosen randomly and evaluated on their general information, social supports, self-efficiency, clinical symptoms, explicit aggressive behavior and detection of serum cortisol, all of which were followed up six months later. Results: The positive symptom, negative symptom and serum cortisol at the first time point were all related to Male schizophrenia patients' aggressive behavior 6 months later. The aggressive behavior, positive symptom and serum cortisol at the first time point were related to Female schizophrenia patients' aggressive behavior 6 months later. Conclusion: The aggressive behavior, positive symptom, negative symptom and serum cortisol are the predictive factors for aggressive behavior in schizophrenia patients.

基金项目：

深圳市科创委（JCYJ20140415090253911）

作者简介：

参考文献：

1 Caqueo-Urízar A, Fond G, Urzúa A, et al. Violent behavior and aggression in schizophrenia:Prevalence and risk factors. A multicentric study from three Latin-America countries. Schizophrenia Research, 2016
2 Kö?ger F, E?sizog?lu A, Sönmez ?, et al. The Relationship between Violence and Clinical Features, Insight and Cognitive Functions in Patients with Schizophrenia. Turk Psikiyatri Derg, 2016, 27(2):
3 Chen Q, Zhou J. Aggression of Chinese inpatients with schizophrenia:a systematic literature review. Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2012, 37(7):752-756
4 Zhou JS, Zhong BL, Xiang YT, et al. Prevalence of aggression in hospitalized patients with schizophrenia in China:A meta-analysis. Asia-Pacific Psychiatry, 2016, 8(1):60-69
5 McBurnett K, Lahey BB, Rathouz PJ, et al. Low salivary cortisol and persistent aggression in boys referred for disruptive behavior. Archives of General Psychiatry, 2000, 57(1):38-43
6 Shoal GD, Giancola PR, Kirillova GP. Salivary cortisol, personality, and aggressive behavior in adolescent boys:a 5-year longitudinal study. Journal of the American Academy of Child & Adolescent Psychiatry, 2003, 42(9):1101-1107
7 Poustka L, Maras A, Hohm E, et al. Negative association between plasma cortisol levels and aggression in a high-risk community sample of adolescents. Journal of Neural Transmission(Vienna), 2010, 117(5):621-627
8 Platje E, Jansen LM, Raine A, et al. Longitudinal associations in adolescence between cortisol and persistent aggressive or rule-breaking behavior. Biological Psychology, 2013, 93(1):132-137
9 Martin CG, Kim HK, Bruce J, et al. Child diurnal cortisol rhythms, parenting quality, and externalizing behaviors in preadolescence. Psychoneuroendocrinology, 2014, 40(1):170-180
10 Pfattheicher S, Keller J. Towards a biopsychological understanding of costly punishment:the role of basal cortisol. PLoS One, 2014, 9(1):e85691
11 Stoppelbein L, Greening L, Luebbe A, et al. The role of cortisol and psychopathic traits in aggression among at-risk girls:tests of mediating hypotheses. Aggressive Behavior, 2014, 40(3):263-272
12 van der Meij L, Klauke F, Moore HL, et al. Football fan aggression:the importance of low Basal cortisol and a fair referee. PLoS One, 2015, 10(4):e0120103
13 Abel KM, Drake R, Goldstein JM. Sex differences in schizophrenia. International Review of Psychiatry, 2010, 22(5):417-428
14 汪向东, 王希林, 马弘. 心理卫生评定量表手册. 北京:中国心理卫生杂志社出版, 1999
15 张作记. 行为医学量表手册. 北京:中华医学电子音像出版社, 2005
16 van Dongen JD, Buck NM, van Marle HJ. Positive symptoms, substance use, and psychopathic traits as predictors of aggression in persons with a schizophrenia disorder. Psychiatry Research, 2016, 237:109-113
17 Sisek-Šprem M, Kri?aj A, Jukic' V, et al. Testosterone levels and clinical features of schizophrenia with emphasis on negative symptoms and aggression. Nordic Journal of Psychiatry, 2015, 69(2):102-109
18 Bulgari V, Iozzino L, Ferrari C, et al. Clinical and neuropsychological features of violence in schizophrenia:A prospective cohort study. Schizophrenia Research, 2016
19 Raine A. Biosocial studies of antisocial and violent behavior in children and adults:a review. Journal of Abnormal Child Psychology, 2002, 30(4):311-326
20 Brown LL, Tomarken AJ, Orth DN, et al. Individual differences in repressive-defensiveness predict basal salivary cortisol levels. Journal of Personality and Social Psychology, 1996, 70(2):362-371
21 Blair C, Peters R, Granger D. Physiological and neuropsychological correlates of approach/withdrawal tendencies in preschool:further examination of the behavioral inhibition system/behavioral activation system scales for young children. Developmental Psychobiology, 2004, 45(3):113-124
22 Dietrich A, Riese H, van Roon AM, et al. Temperamental activation and inhibition associated with autonomic function in preadolescents. The TRAILS study. Biological Psychology, 2009, 81(1):67-73
23 van Honk J, Harmon-Jones E, Morgan BE, et al. Socially explosive minds:the triple imbalance hypothesis of reactive aggression. Journal of Personality, 2010, 78(1):67-94
24 Tops M, Boksem MA. Cortisol involvement in mechanisms of behavioral inhibition. Psychophysiology, 2011, 48(5):723-732
25 van Honk J, Tuiten A, van den Hout M, et al. Baseline salivary cortisol levels and preconscious selective attention for threat. A pilot study. Psychoneuroendocrinology, 1998, 23(7):741-747
26 van Honk J, Tuiten A, van den Hout M, et al. Conscious and preconscious selective attention to social threat:different neuroendocrine response patterns. Psychoneuroendocrinology, 2000, 25(6):577-591

服务与反馈：

【文章下载】【加入收藏】