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男性海洛因吸食者不同戒断时相对认知功能的影响
作者:杨玲  周艳艳  苏波波  张建勋  赵鑫 
单位:西北师范大学心理学院  兰州730070 
关键词:戒断时相 海洛因戒断者 冲突适应 认知功能 
分类号:R395.1
出版年,卷(期):页码:2015,23(6):968-971
摘要:

目的:本研究以冲突适应作为有效指标来测查不同戒断时相男性海洛因吸食者认知功能的恢复水平。方法:用字母Flanker任务对海洛因戒断1个月、6个月及1年的三个实验组和控制组各33名施测来探讨个体试次间调整(trial-to-trial adjustments)的反应时之差(即RT(cI-iI))的变化特点。结果:①四组被试RT(I)均显著长于RT(C),Flanker冲突效应(RT(I-C))没有组间差异;控制组RT(cI)显著长于RT(iI),而1月组RT(iI)显著长于RT(cI),进一步检验发现控制组的RT(cI-iI) 显著大于1月组和6月组。②1月组和1年组在奖赏性药物渴求感上得分均显著高于6月组。结论:①海洛因戒断1年组经历冲突后能够调整认知资源和策略来更好地“适应”冲突。②戒断者对海洛因的渴求感在戒断期内持续存在,可能存在“埋伏”现象。

Objective: To investigate the recovery level of cognitive function of heroin abstainers among different with-drawal phases and puts the“adapt”conflict as an effective indicator. Methods: Using the Flanker task with letters, this re-search examined the changing characteristics of“adapt”conflict in 99 male haroin abstainers during different withdrawal phases(withdrawal one month, six months and one year, 33 participants respectively) and control group(33 subjects). Re-sults: ①Analyses revealed main effect of congruent type on response time, in all groups, RTs(I) were significantly longer than RTs(C). There was also a significant interactive effect between group and trial-to-trial adjustment, the further simple effect test found that significant main effect of trial-to-trial adjustment in control group and 1 month group. The trial-to-tri-al adjustments RT effect(cI-iI) differed significantly among the three heroin groups and controls. ②Reward drug craving feelings in both 1 month and 1 year group were significantly higher than that in 6 months group on. Moreover, depression score in 1 month group was markedly higher than that in 6 months and 1 year group. Conclusion: These findings suggest that after 1 year withdrawl of drug, the heroin abstainers can ajust their cognitive resources and strategies to cope with“con-flict”, however, the heroin craving still persist during withdrawal period in heroin abstainers.

基金项目:
国家自然科学基金(31360233,31300838) 和教育部人文社会科学研究一般项目(13YJC190032)
作者简介:
参考文献:

1 Salo R, Ursu S, Buonocore MH, et al. Impaired prefrontal cortical function and disrupted adaptive cognitive control in methamphetamine abusers: A functional magnetic resonance imaging study. Biological Psychiatry, 2009, 65(8): 706-709
2 Botvinick MM, Braver TS, Barch DM, et al. Conflict monitoring and cognitive control. Psychological Review, 2001, 108 (3): 624-652
3 Botvinick MM. Conflict monitoring and decision making: Reconciling two perspectives on anterior cingulate function. Cognitive, Affective, and Behavioral Neuroscience, 2007, 7 (4): 356-366
4 Ullsperger M, Bylsma LM, Botvinick MM. The conflict adaptation effect: It's not just priming. Cognitive, Affective, and Behavioral Neuroscience, 2005, 5(4): 467-472
5 Salo R, Fassbender C, Buonocore MH, et al. Behavioral regulation in methamphetamine abusers: An fMRI study. Psychiatry Research: Neuroimaging, 2013, 211(3): 234-238
6 Hester R, Nestor L, Garavan H. Impaired error awareness and anterior cingulate cortex hypoactivity in chronic cannabis users. Neuropsychopharmacology, 2009, 34: 2450-2458
7 Battisti RA, Roodenrys S, Johnstone SJ, et al. Chronic cannabis users show altered neurophysiological functioning on Stroop task conflict resolution. Psychopharmacology, 2010,212: 613-624
8 Bell RP, Foxe JJ, Ross LA, et al. Intact inhibitory control processes in abstinent drug abusers(I):A functional neuroimaging study in former cocaine addicts. Neuropharmacology,2014, 82: 143-150
9 Li C-SR, Milivojevic V, Kemp KA, et al. Performance monitoring and stop signal inhibition in abstinent patients with cocaine dependence. Drug and Alcohol Dependence, 2006,85(3): 205-212
10 Rabbitt PMA. Errors and error correction in choiceresponse tasks. Journal of Experimental Psychology, 1966,71(2): 264-272
11 Zhang XL, Shi J, Zhao LY, et al. Effects of stress on decision-making deficits in formerly heroin-dependent patients after different durations of abstinence. The American Journal of Psychiatry, 2011, 168(6): 610-616
12 Wang GB, Zhang XL, Zhao LY, et al. Drug-related cues exacerbate decision making and increase craving in heroin addicts at different abstinence times. Psychopharmacology,2012, 221(4): 701-708
13 周平艳,周仁来,惠颖,等. 不同戒断期海洛因戒断者情绪加工的损伤和恢复. 心理学探新,2014,34(2):172-178
14 Li C-SR, Luo X, Sinha R, et al. Increased error-related thalamic activity during early compared to late cocaine abstinence. Drug and Alcohol Dependence, 2010, 109(1-3): 181-189
15 Dilleen R, Pelloux Y, Mar AC, et al. High anxiety is a predisposing endophenotype for loss of control over cocaine, but not heroin, selfadministration in rats. Psychopharmacology,2012, 222(1): 8997
16 Leschka S, Fornaro J, Laberke P, et al. Differentiation of cocaine from heroine body packs by computed tomography: Impact of different tube voltages and the dual-energy index. Journal of Forensic Radiology and Imaging, 2013, 1(2): 46-50
17 Verdejo-García AJ, Perales JC, Pérez-García M. Cognitive impulsivity in cocaine and heroin polysubstance abusers. Addictive Behaviors, 2007, 32(5): 950-966
18 连智,刘志民. 阿片成瘾严重程度量表的初步编制与信度测试. 药物流行病学杂志,2003,12(2):85-88
19 罗勇. 戒毒人员脱毒期药物渴求的调查研究. 西南师范大学硕士学位论文,2004
20 Gratton G, Coles MG, Donchin E. Optimizing the use of information: Strategic control of activation of responses. Journal of Experimental Psychology: General, 1992, 121(4): 480-506
21 Gibson EJ. Principles of Perceptual Learning and Development. New York: Appleton-Century-Crofts, 1969
22 Kan IP, Teubner-Rhodes S, Drummey AB, et al. To adapt or not to adapt: The question of domain-general cognitive control. Cognition, 2013, 129(3): 637-651
23 Verguts T, Notebaert W. Adaptation by binding: A learning account of cognitive control. Trends in Cognitive Sciences,2009, 13(6): 252-257
24 Notebaert W, Verguts T. Conflict and error adaptation in the Simon task. Acta Psychologica, 2010, 136(2): 212-216
25 Streeter CC, Terhune DB, Whitfield TH, et al. Performance on the Stroop predicts treatment compliance in cocainedependent individuals. Neuropsychopharmacology, 2008,33: 827-836
26 邬志美,郭田生. 海洛因依赖者稽延性戒断症状的动态变化. 中国药物滥用防治杂志,2006,12(4):194-196

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