中国临床心理学杂志

首发未用药混合型强迫症患者抑制控制障碍对其社会功能的影响

单位：1 广东省医学科学院广东省人民医院广东省精神卫生中心广州 510080
2 广州市脑科医院广州 510370
3 广州医学院附属第一医院广州 510120

分类号：R395.2

出版年,卷(期):页码：2013,21(4):589-591

摘要：

目的:探讨首发未用药强迫思维混合强迫行为型强迫症患者抑制控制障碍对社会功能的影响。方法:根据耶鲁-布朗强迫量表(YBOCS)及汉密尔顿抑郁量表(HAMD)纳入混合型强迫症患者40例,纳入正常对照者40例。采用威斯康星卡片分类测验(WCST)、连线测验(TMT)、Stroop测验评定患者组和对照组抑制控制功能,同时使用社会功能缺陷量表(SDSS)评定社会功能水平。结果:①患者组Stroop测验中读字色(Stroop-CW)的正确数和错误数成绩明显差于正常组;连线测验B(TMT-B)完成时间、连线测验A(TMT-A)完成时间长于正常对照组;WCST测验中患者组WCST完成分类数、正确应答数两项成绩均低于正常对照组;患者组社会功能缺陷总分明显高于正常组;②多元回归分析显示,患者组Stroop-CW正确数、Stroop-CW错误数、TMT-B完成时间对其社会功能有显著影响(P<0.05)。结论:首发未用药混合型强迫症患者抑制控制功能越差,社会功能受损越严重。

Objective: To explore the effect of inhibitory control of drug-free patients with obsessive-compulsive disorder on social function. Methods: Forty patients with mixed OCD were recruited according to YBOCS and HAMD, also 40 normal controls were recruited. WCST, TMT and Stroop test were used to assess the inhibitory control function. SDSS was used to assess social function level. Results: ①Both accurate and error scores of color-word in Stroop test in patient group were significantly lower than that of normal control. The WCST categorization score and accurate answer score were lower than that in normal control. Complete time of TMT-A and TMT-B were longer than that of normal control. The patients group also had higher score in SDSS. ②With multiple regression analysis, the score of accurate number in Stroop-CW, and error score in Stroop-CW, TMT-B complete time were found to predict the score of SDSS (P＜0.05). Conclusion: The inhibitory control function in first-onset drug-free patients with mix subtype OCD could predict their social functioning, the lower their inhibitory control is, the worse their social functioning is.

基金项目：

广东省医学科研基金资助项目(B2013006)

作者简介：

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